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Re: olden_grumpini post# 357529

Friday, 04/30/2021 1:10:17 PM

Friday, April 30, 2021 1:10:17 PM

Post# of 402939
If you had been paying attention you would realize all the antiviral being tested for moderate to severely ill Covid19 patients have failed to reduce mortality or complications of Covid 19. These medications include Remdesivir, Favipiravir, Molunpiravir,Regeneron's and Lilly's monoclonal antibodies and others.

Now many of these medications are being tested in the mild Covid patients to see if they reduce the chance of progression to moderate or severe disease.

Will the Pfizer pill for Covid19 be effective when other IV protease inhibitors, lopinavir and ritonavir, have completely failed?

Brilacidin is being tested for the as a Covid 19 antiviral for the moderate to severe disease patients. If it is successful it will have virtually no competition. Most moderately to severely ill patients ideally should have a antiviral as a part of their therapeutic regimen.

As you should know Brilacidin has advantages over all the antivirals studied to date. It is the only virucidal antiviral. It begins killing Covid in the serum, extracellular space and inside the cells on contact. Its is active immediately where many of the other drugs such as Remdesivir have to be converted to an active form inside the cells. It is the only well documented anti-inflammatory antiviral. Brilacidin may possess a triple antiviral mechanism of action. It shreds the viral capsid, prevents viral cellular attachment and may be active against the main protease to prevent viral reproduction. It is a broad spectrum antibiotic with activity against most Gram positive bacteria including MRSA as well as some gram negative bacteria which will reduce the chance of secondary infections such as pneumonia and septicemia in these ill patients.

It should be obvious that the vaccines are never going to be 100% effective, Covid mutates frquently reducing the effectiveness of the vaccines and millions of individuals will never take the vaccines.

It is also obvious Covid19 with its deaths and side effects is not going away even with vaccines and preventative treatments.

Unfortunately a market for an effective Covid19 antiviral is going to be needed because death and morbidity from Covid is going to be with us .

GLTA Farrell

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