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Re: C-20 post# 162224

Wednesday, 04/28/2021 4:52:24 PM

Wednesday, April 28, 2021 4:52:24 PM

Post# of 233221

how is heeling one out of 4 that are S2C failing it’s trial


It doesn't heal 1 out of 4. That is the relative benefit, not the absolute benefit. Critical patients in the leronlimab arm had a 38% mortality. Critical patients in the placebo arm had a 47% mortality rate. 47% is 24% larger than 38% but it is an absolute benefit of 9%.

There were 62 critical patients. If 2 more placebo patients had survived, the placebo arm would have had a lower mortality percentage than the leronlimab arm. In other words, the mortality benefit is likely due to random luck.
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