I have never heard of a DSMB recommending that the trial stop enrollment and add a 12 month follow-up window to keep the same power.
In the proper sense, all keeping the same power means is that they expect the same number of events. If so, this could be no more that NVCR saw that enrollment was so slow they might as well just wait the 12 months than keep trying to enroll.
In the best sense, the DSMB sees the curves separating so well that they know they have sufficient patients and only need time to collect AEs.
In the worst case, the DSMB just called for a futility halt and NVCR is spinning it. In the cases where a futility halt happens before enrollment is complete. the trial can continue but it is unethical to enroll more patients. An that does match what just happened.
Recent NVCR News
- Novocure to Present Real-World Data at ESMO 2024 Demonstrating Improved Survival Outcomes for Newly Diagnosed Glioblastoma Patients with Increased Use of Tumor Treating Fields (TTFields) Therapy • Business Wire • 09/09/2024 11:00:00 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 09/03/2024 11:00:17 AM
- Novocure Announces Planned CEO Transition • Business Wire • 09/03/2024 11:00:00 AM
- Novocure to Participate in 2024 Wells Fargo Healthcare Conference • Business Wire • 08/28/2024 11:00:00 AM
- Novocure Highlights TTFields Therapy in Treatment of Non-Small Cell Lung Cancer at 2024 World Conference on Lung Cancer • Business Wire • 08/14/2024 11:00:00 AM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 08/06/2024 08:22:13 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 08/06/2024 08:19:58 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 08/06/2024 08:19:03 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 08/06/2024 08:17:56 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 08/06/2024 08:16:26 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 08/05/2024 08:25:19 PM
- Form S-8 POS - Securities to be offered to employees in employee benefit plans, post-effective amendments • Edgar (US Regulatory) • 07/25/2024 12:25:38 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 07/25/2024 11:05:37 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 07/25/2024 11:01:22 AM
- Novocure Reports Second Quarter 2024 Financial Results • Business Wire • 07/25/2024 11:00:00 AM
- Novocure to Report Second Quarter 2024 Financial Results • Business Wire • 07/01/2024 11:00:00 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 06/10/2024 08:09:16 PM
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