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Monday, 04/12/2021 10:28:11 AM

Monday, April 12, 2021 10:28:11 AM

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AAGP Could Provide a Pathway to Treating This Chronic Autoimmune Disorder

Sjogren’s syndrome is an autoimmune condition in which a body’s own immune system attacks the cells in the moisture-producing salivary glands and tear ducts. The outcome of this autoimmune response is painfully dry eyes and mouth.

Linked to conditions such as rheumatoid arthritis, the condition may occur in tandem with other autoimmune disease or show up on its own. In addition to affecting the eyes and mouth, Sjogren’s can also affect the skin, hair, kidneys, and liver, causing conditions ranging from cavities to cirrhosis.

The two main symptoms of Sjogren's syndrome are:

Dry eyes. Your eyes might burn, itch, or feel gritty — as if there's sand in them.
Dry mouth. Your mouth might feel like it is full of cotton, making it difficult to swallow or speak.

The causes of Sjogren’s syndrome:

It appears that Sjogren’s, like other autoimmune disorders, is caused by a combination of genetic and environmental effects, possibly triggered by an infection, according to the Mayo Clinic. However, it’s unclear why some people are affected by the disease when others are not.
Autoimmune diseases are complex systems, but researchers are homing in on several risk factors for Sjogren’s: women are more likely than men to have it, as are people over 40 and those who also have a rheumatic disease such as lupus or rheumatoid arthritis.

My (scoobey-do) thought for the day

Research scientist soak eye cells in PKTX’s AAGP and then implant the eye cells into the Patient with Sjogren’s syndrome. The autoimmune system no longer recognizes the cells, in the moisture-producing salivary glands and tear ducts, as ones to be attacked. The eyes continue to produce tears to keep the eyes moist.

Sjogren’s has no known cure

Sjogren syndrome is estimated to affect 4 million people across the United States. Using AAGP, ProtoKinetix is exploring revolutionary new treatments that could alleviate the suffering caused by severe dry eyes.

Go PKTX! Go AAGP! Go Clarence Smith!
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