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Friday, 04/09/2021 4:46:48 PM

Friday, April 09, 2021 4:46:48 PM

Post# of 113754
Pfizer VS SBFM COVID Tablet

Pfizer one of the Three Leading Contenders named in the article.


Same Target as SBFM

Pfizer, now in the earliest stages of human testing, could address that problem. Catchily named PF-07321332, Pfizer’s drug targets SARS-CoV-2’s backbone enzyme, the linchpin of the virus’s replication process. That enzyme, called 3CL, is one of two that are specific to all coronaviruses.



SBFM's Target

One of these functional proteins is a cysteine protease referred to as the main protease (Mpro, also called 3CLpro and nsp5). Mpro cleaves the viral ‘polyproteins’ at a number of specific sites thereby generating a multi-subunit protein complex termed ‘viral replicase-transcriptase’. Because of its functional indispensability in viral replication, Mpro is an attractive drug target for the development of a treatment for COVID-19 and other Coronavirus infections,” said Dr. Slilaty.





Good Reason to have patent protection


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