Thursday, April 08, 2021 2:15:32 PM
“Conclusion: Fa2N-4 cells performed much like fresh human hepatocytes. Using a panel of inducers, both mRNAs and P450 enzymatic activities were induced. These immortalized cells have potential for use as an alternative to primary human liver tissue for In Vitro Induction Studies.”
Finally, immortalized hepatocytes represent the only commercially practical method of supplying cells for a bioartificial liver...
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