Sorrento Therapeutics Inc (SRNE)

[1776club]

Binding antibody detection: These tests use purified proteins of SARS-CoV-2, not live virus, and can be performed in lower biosafety level laboratories (e.g., BSL-2). With specific reagents, individual antibody types, like IgG, IgM, and IgA, can be determined. Although scientists do not know how long antibodies to SARS-CoV-2 can be detected, for most other infections, IgM is most useful for determining recent infection as it usually becomes undetectable weeks to months following infection, while IgG may remain detectable for months or years. IgA is important for mucosal immunity and can be detected in mucous secretions like saliva in addition to blood, though its significance in this disease is still to be determined. Depending on the complexity of assays, these tests can be performed rapidly (in less than 30 minutes) in a field setting or in a few hours in a laboratory.Tests that detect binding antibodies fall into two broad categories.
Point-of-care (POC) tests generally are lateral flow devices that detect IgG, IgG and IgM, or total antibody in serum, plasma, whole blood, and/or saliva. An advantage of some point-of-care tests using whole blood is that they can be performed on blood samples obtained by fingerstick rather than venipuncture.