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Saturday, February 27, 2021 7:33:38 PM
That’s because the standard of care can vary greatly from case to case and doctor to doctor. It’s the attending physician’s decision on what treatments. It’s the physician’s knowledge of possible counter-indications for the patient’s needs that both determines a patient’s needs as well as adjusts symptoms and severity presented. For example, for mild to moderate COVID-19 steroids are not recommended, while severe cases they are strongly recommended, case by case.
Moreover, there was already a large body of phase 3 evidence for Remdesivir and corticosteroids against severe respiratory distress as that is the SOC for hospitalized influenzas, which have similar symptoms to severe SARS-CoV. So, it’s up to the attending physician to know all that. Even more, the SOC has rapidly changed and updated over this past year with FDA recommended protocols and treatment changes more than monthly. Clinical site doctors are expected to keep up with those changes and adjust accordingly.
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