Relief Therapeutics Holding AG (RLFTF)

[changes_iv]

Zyesami(TM), GOOD FAST

According to a user from the United Kingdom, the name Zye means "Thanks". According to a user from the United States, the name Zye is of American origin and means "Good fast". A user from Mississippi, U.S. says the name Zye is of African American origin and means "Never leave my side". ~ NAME.org ————————————

NeuroRx has reported that the Phase IIb/III trial of Zyesami (aviptadil, previously RLF-100) showed multidimensional benefit in treating respiratory failure in critically ill Covid-19 patients.

It was initially approved as a 28-day study at the FDA’s guidance but NeuroRx added a 60-day endpoint last December.

The move comes after recognising that the traditional 28-day endpoint adopted in the 1990s for trials in Acute Respiratory Distress Syndrome is not suitable for critically ill Covid-19 patients as they are admitted in the ICU with modern technologies well beyond this period of time.

NeuroRx and some clinical trial sponsors informed the FDA on this trend and the FDA has published formal guidance altering the time needed for evaluating the prespecified endpoint of ‘alive and free of respiratory failure’ in critically ill patients to 60 days.

https://www.clinicaltrialsarena.com/news/neurorx-zyesami-recovery-trial/