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Tuesday, February 23, 2021 10:23:19 AM
Ok, from that same link
So you're right, not only is it a target, it is apparently one that can be introduced.
Counteracting the Subversion of Antigen Presentation
Several methods have been considered to maximize antigen presentation. For instance, tumor cells expressing MHC molecules are being used as vaccines. However, the more common approach is to transfer natural or artificial APCs that have been manipulated in vitro to display defined antigens (loaded under controlled conditions). Other in vivo approaches are being developed to limit the manipulations of host cells and to avoid cumbersome personalized immunotherapy. In this last section, we will address the needs to discover additional TAAs, improve cellular vaccines and define alternative methods to effectively stimulate CD4+ T cells.
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