Algernon Pharmaceuticals Inc (AGNPF)

[medchem]

Finally! Some discussion!

Point 1: Independently reviewed by who? Who made the decision to increase the sample size to try and find signal? The executives did. Why not start a new trial? They have chronic cough running, and if they believed Phase 3 covid had a chance, you would think they would focus on that. But what's most important as a red flag is the timing. They dropped prelim data news which was a flop, and shortly thereafter planned a new phase 1. thats the red flag. its classic, pump the SP up before dropping the final news (flop).

2. what you're proposing is that there be no accountability. are they free to pay themselves ANYTHING. They make zero profits, thus they should be paying themselves much less than they are (400k... are you kidding, with no revenues, using money they fundraised :O through dilution at YOUR expense...)

3. they have changed the number of patients in the data readout to find signal, and delayed the final results ... if the trial was completed before this fire, than why is the readout being delayed? Proof of the fire?

4. There's only so much time in the day. Running a pharma company takes A LOT of time. This further supports my point about the execs being over paid. You think mark williams deserves hundreds of thousands of dollars for working at Algernon making no revenue and also spending his time (what %?) at his own (separate) company?

5. You are speaking as a non-scientist. In science, if you say you will read out using x number of patients, and you manipulate that because x patients didn't find signal... that's unethical and simply a ref flag of whats to come in the final readout.

6. Dilute and dilute ... but the fact is that hitting the jackpot in penny land is rare and more likely you will be diluted to dirt. Most of us who have been around since breathtec understand, these guys dilute and dilute and have NEVER generated a single dollar... university of florida who?

7. I don't prefer pumping. I guess just compensating for no revenues and a flopped prelim data readout....

I'm getting tired of hearing the same repeated negative garbage over and over so I'm going to provide some.... OTHER POSSIBLE VIEWS.

1. Why on earth would they not start new trials as they previously stated they would for 2021. Do you suggest everyone working at Algernon should just sit back doing nothing while awaiting results that are being INDEPENDENTLY REVIEWED? You later state money is being wasted by this organization yet you want them to sit around doing nothing getting paid? Contradiction.

2. Why would management not pay themselves well? Maybe you don't think they're worth their salaries, but do you know if they work 20 hours a week or 80? I venture a guess neither you nor I have any idea how hard they're working. Maybe to keep a good team on board a good salary is required?

3. Enrollment is enrollment, if there's not enough patients for your trial it is slowed down.... nothing can be done about this unless they find more hospitals that may have more patients. I hope you're only talking about delays that are Algernon's own fault here? Surely you aren't pissed off at the 5 people who died in a hospital fire slowing the growth of your bank account? Takes a special kind of....

4. I personally work for companies and do self employed work as well. Does that mean I provide garbage work for the companies?

5. Why on earth would they not provide interim data using all the patient data available. Sure the plan was only 75 patients, but if you have data for more, why not include them to provide a stronger signal? In what world does the fact that the primary endpoints weren't as strong yet some secondary endpoints showed great potential mean the science failed? Have you seen what's available on the market currently? Jokes. Literal jokes are the current treatment. If Ifenprodil saves even 10% of the people who were going to die it would be incredible and used worldwide.

6. Dilution is the name of the game in all penny stocks. If Ifenprodil is successful and the market reacts strongly, we'll still be laughing all the way to the bank.

7. I can agree a lot of the news releases are fairly fluffy, however would you prefer sitting around not having any idea what's going on? Do you ever read the msg boards or companies that play it that way? It's an absolute sh*show of speculation about what the hell is even going on. I'll take some fluff with my beef any day of the week over radio silence.