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Re: To infinity and beyond! post# 345291

Wednesday, 02/10/2021 2:26:38 PM

Wednesday, February 10, 2021 2:26:38 PM

Post# of 403091
Not sure I'd get too rattled about this one...

Here is an excerpt...

There are limitations to our study. This is an open-labelled study, which was stopped early due to the impact of the national pandemic control measures and national prioritisation rules for clinical research trials in the UK. Our power calculations were made from the best available predictions in early 2020. Therapeutic randomised clinical trial design and sample size calculations are often dictated by statistical assumptions with treatment effect estimations based on the evidence of best available care. However, in trial design for a new disease, with no known effective treatment, statistical assumptions are thus arbitrary.



For those that want to read the study...

https://www.medrxiv.org/content/10.1101/2021.02.04.21251134v1.full-text

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