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Re: Chrism0000 post# 6560

Sunday, 01/24/2021 8:22:02 AM

Sunday, January 24, 2021 8:22:02 AM

Post# of 14113
Perhaps you haven't heard, there are MORE vaccines on the way.

More vaccines = more work for FDA.

Jan. 13, 2021

(Reuters) - Johnson & Johnson is on track to roll out its single-shot coronavirus vaccine in March, and plans to have clear data on how effective it is by the end of this month or early February, the U.S. healthcare company’s chief science officer said.




AstraZeneca is expected to seek approval for their vaccine in the spring. The trial data will need to be carefully scrutinized due to one serious blunder with unexpected results:

The AstraZeneca trial also included at least one big mistake. A subset of trial participants under 55 years old were accidentally administered a half-dose first shot, followed by a full-strength second jab.

"That's a pretty serious error," Dr. Cody Meissner, chief of pediatric infectious disease at Tufts Medical Center, and one of the vaccine experts on the FDA's advisory committee, told Insider of the mishap.

Those patients who had a less potent initial shot, followed by a full-strength booster actually appeared more protected from coronavirus infections, with efficacy surging to 90% in the subgroup. Experts were puzzled by that.

"I won't go to the point of saying that it's not biologically plausible, but it's a little bit odd," Meissner said.

"It generates a little bit of pause, and makes one eager to actually look at the data and see what they found and to understand it a little bit more carefully."


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