Innovation Pharmaceuticals Inc (IPIX)

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Selectivity Index...

“The selectivity index (SI) is a ratio that measures the window between cytotoxicity and antiviral activity by dividing the given AVA value into the TOX value (AVA/TOX). The higher the SI ratio, the theoretically more effective and safe a drug would be during in vivo treatment for a given viral infection. The ideal drug would be cytotoxic only at very high concentrations and have antiviral activity at very low concentrations, thus yielding a high SI value (high AVA/low TOX) and thereby able to eliminate the target virus at concentrations well below its cytotoxic concentration. The selectivity index of a compound is a widely accepted parameter used to express a compound’s in vitro efficacy in the inhibition of virus replication.”

While many are focused on a near-term coronavirus therapy, please keep in mind that Brilacidin’s capabilities would likely extend to other infections as well. Brilacidin has displayed anti-fungal, antibiotic, and antiviral properties. The clock is ticking.

HDMP (Human Defensin Mimetic Proteins) for the win.