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Re: jbog post# 3085

Wednesday, 01/10/2007 11:00:34 AM

Wednesday, January 10, 2007 11:00:34 AM

Post# of 4764
Merck News Release

Merck KGaA: Erbitux Meets Primary Endpoint in First-Line Phase III
Metastatic Colorectal Cancer Study


Darmstadt, Germany, January 10, 2007 – Merck KGaA announced today that a
Phase III study of Erbitux® (cetuximab) plus irinotecan-based therapy met
the primary endpoint of increasing median duration of progression-free
survival in patients with previously untreated metastatic colorectal cancer
(mCRC). This randomized Phase III international trial, known as CRYSTAL
Cetuximab combined with iRinotecan in first line therapY for metaSTatic
colorectAL cancer, studied patients treated with Erbitux plus FOLFIRI
(irinotecan-based chemotherapy) compared with FOLFIRI alone.

The complete news release can be downloaded at the following link:
http://me.merck.de/n/5BE1C55BDCA32E01C125725E004DFBE1/$FILE/crystal_e.pdf

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