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Re: SF Anony post# 141063

Sunday, 01/17/2021 10:02:33 AM

Sunday, January 17, 2021 10:02:33 AM

Post# of 233415
If that were the case, it is litteraly NOT a sample size reassesment.

Technically, this is a statistical significance test. You test if you can reject the null hypothesis H0 (that the treatment has no effect against standard of care).

Not the same at all (and not the same math. procedure even if both are not hard to perform).

They didn't write that they wanted the new 75% interim to perform again a statistical significance test. They wrote, and these are very specific words, that they wanted to perform a sample size reassessment.

I am a statistician and such technical words have a precise meaning.
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