Humanigen Inc (HGENQ)

[Knuckle Sandwich]

Very interesting tweet stream from Dr. Matt McCarthy. I've combined them together to make it easier to read. Link is at bottom of page.

As COVID medicine evolves, we may similarly turn to drugs that decrease vessel inflammation (immunomodulators) instead of blood thinners to treat clots. This year, we will test all sorts of immunomodulators on #COVID patients, including lenzilumab, risankizumab, and anakinra.

This week, I randomized someone to the cenicriviroc arm of a #COVID19 immunomodulator study. It's a drug I had never heard of until recently. But the trial might help explain why blood vessels become inflamed and clots form. It could turn conventional thinking on its head.


Takeaway: We're using blood thinners to treat COVID clots, but that may change. Immunomodulators could be a better option.
Soon we will solve one of the enduring mysteries of the pandemic: Why do some #COVID patients develop life-threatening blood clots and how can we save them?

As COVID medicine evolves, we may similarly turn to drugs that decrease vessel inflammation (immunomodulators) instead of blood thinners to treat clots. This year, we will test all sorts of immunomodulators on #COVID patients, including lenzilumab, risankizumab, and anakinra.

— Matt McCarthy (@DrMattMcCarthy) January 15, 2021