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Re: olden_grumpini post# 338590

Monday, 01/04/2021 7:58:09 AM

Monday, January 04, 2021 7:58:09 AM

Post# of 403079
There is some evidence that Covid causes arterial damage, at least affecting the brain.

"Wednesday, December 30, 2020

NIH study uncovers blood vessel damage and inflammation in COVID-19 patients’ brains but no infection

Results from a study of 19 deceased patients suggests brain damage is a byproduct of a patient’s illness."


https://www.nih.gov/news-events/news-releases/nih-study-uncovers-blood-vessel-damage-inflammation-covid-19-patients-brains-no-infection

I would assume that other organs, such as the lungs, could be similarly affected, but I don't have any information to substantiate that. However, patients with hypertension may already have constricted pulmonary arteries, and a further deterioration of those arteries from Covid infection only makes the onset of ARDS the more likely.

So to me, it makes sense to exclude patients with hypertension from the trial population.

From the power point presentation you linked, I didn't see that a co-therapy was used with brilacidin. But am I correct in thinking that the company is now using remdesivir as a co-therapy? It appears one is needed to assist brilacidin in attacking both infection and inflammation.

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