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Sunday, January 03, 2021 10:36:25 AM
In my mind, the in vitro testing is somewhat irrelevant since I assume that all drugs moving into clinical trials have had successful in vitro testing. The past IV administration of brilacidin is problematic because of the significant adverse events, especially hypertension. Perhaps I’m mistaken, but I assume hypertension is unwelcome in patients suffering from ARDS.
From your experience, is it likely that a hospital administrator would be willing to put their neck on the block and devote resources to a clinical trial of brilacidin? Some posters seem to believe that they will want to be associated with the gold standard/COVID killer, but my assumption is that they tend to be risk averse and more afraid of lawsuits and bad publicity.
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