SGN-40 and Rituxan appear to be synergistic in NHL models. They will test it in aggressive NHL as a single-agent, in combo with R-ICE in 2nd-line, in combo with Rituxan in 3rd-line, and in combo with R-CHOP in 1st-line. SGEN also plans to conduct a combo Revlimid/SGN-40 study in MM.
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