Adaptimmune Therapeutics PLC (ADAP): The next product into the clinic (for HC...

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Re: NY1972 post# 121

Friday, 12/18/2020 3:24:40 PM

Friday, December 18, 2020 3:24:40 PM

The next product into the clinic (for HCC) will contain CD8a co-receptors https://s3.amazonaws.com/content.stockpr.com/adaptimmune/files/pages/adaptimmune/db/212/content/Anderson+et+al+-+MAGE-A4+Preclinical+poster+FINAL.pdf

So that should improve the depth and duration of response. I also know a low-dose radiotherapy sub-study is going, and that could be incorporated during lymphodepletion https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(18)30449-0

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