Once people catch on to the fact that Mary's holds the patent on Transdermal technology, this is game over.
Advantages of transdermal cannabis patches
Patches have long been used by the pharmaceutical industry to deliver compounds, including nicotine, estrogen, testosterone, the high-blood pressure medication clonidine, and the heart drug nitroglycerine. The mechanism is always the same: the patch is applied to the skin and the drug seeps into the bloodstream.
The direct-to-bloodstream path offers several advantages over other forms of cannabis consumption. For starters, delivery of the active ingredients is slow and steady. “With inhaling,” Riggle said, “you get a high dose right away, which your body metabolizes quickly. There's instant stimulation of the endocannabinoid system [ECS]. With slower, prolonged delivery, you can get the endocannabinoid system to where it's functioning optimally.”
Secondly, patches don't have the toxic byproducts of consumption methods such as smoking or vaping.
Transdermal patches also offer a key benefit over oral methods of consumption — tinctures, edibles, or sublingual sprays, strips, or drops. Consuming cannabis orally is what's known in pharmacology as “first-pass metabolism.” That means the active ingredient passes through your digestive system and then your liver before it reaches its intended destination; in the case of cannabis products, that's the ECS. As a result of that first pass, potency is greatly reduced. “If you orally consume 10 milligrams of THC or CBD, roughly half of that will be metabolized during a first pass,” Riggle said. Transdermal patches sidestep that dilution.
One final advantage: better control. “You can find out what dose works best for you,” Riggle said, “and then get the same precise dose every time
