BrainStorm Cell Therapeutics Inc (BCLI)

[midastouch017]

BrainStorm Announces Completion of All Dosing in NurOwn® Phase 2 MS Study

Fri, December 18, 2020, 2:00 PM GMT+2

Topline clinical trial results expected by the end of the first quarter 2021

NEW YORK, Dec. 18, 2020 /PRNewswire/ -- BrainStorm Cell Therapeutics Inc. (NASDAQ: BCLI), a leading developer of adult stem cell therapies for neurodegenerative diseases, announced today that all dosing has been completed in the ongoing Phase 2 trial evaluating NurOwn® (MSC-NTF cells) as a treatment for progressive MS. The Phase 2 open-label clinical trial of repeat-dosing CSF-delivered autologous MSC-NTF cells (NurOwnâ) is being conducted at five clinical trial sites in the United States.

"Completed dosing of the Phase 2 progressive MS clinical trial is a major milestone for BrainStorm as we advance our goal to develop the NurOwn platform technology in neurodegenerative diseases," said Chaim Lebovits BrainStorm CEO. "We are very thankful for the dedicated efforts of the investigators and their teams and to the patients who participated in this important clinical trial. Through their combined efforts, we hope to bring a promising therapeutic option to those affected by progressive MS."

Ralph Kern MD, MHSc BrainStorm President and Chief Medical Officer commented, "Now that all dosing of the NurOwn Phase 2 progressive MS clinical trial is complete, we will shift our focus to completing all remaining patient clinical trial assessments and biomarker analyses. We look forward to generating clinical trial top line results by the end of the first quarter 2021 and to advancing this promising treatment option based on a thorough analysis of the clinical trial outcomes."

Stacy Lindborg PhD, EVP and Head of Global Clinical Research at BrainStorm added, "Detailed analyses of the full study data set at the conclusion of the trial will add to our understanding of the potential of NurOwn technology in progressive MS and to the growing body of evidence for NurOwn in neurodegenerative disease. The data and scientific insights we will share with the MS scientific community at upcoming conferences and in subsequent publications will help advance understanding of progressive MS and the potential benefits of NurOwn as a treatment."

MS is a chronic neuroinflammatory and neurodegenerative disorder that affects the brain and spinal cord. MS affects approximately 1 million individuals in the U.S. and 2.5 million individuals worldwide. Approximately half of affected individuals will eventually develop a progressive form of the disease, which may lead to increasing levels of motor, visual, and cognitive functional impairment, and disability.

https://finance.yahoo.com/news/brainstorm-announces-completion-dosing-nurown-120000389.html