Monday, November 16, 2020 10:43:20 PM
First hint is under Aarthi Narayanan at GMU in vitro Brilacidin studies confirmed one of the mechanisms of action is the virucidal effect of Brilacidin against Cornavirus.
Hint number 2 is this section of the report is titled "Rising to the Covid-19 challenge" pg 297 with Aarthi Narayanan featured under the title.
Hint 3 is the title of the page 307 is Case 2: Antiviral peptides and synthetic peptidomimetics against human coronaviruses –GMU...
To the best of my knowledge Brilacidin is the only synthetic peptidomimetic studied as a treatment against Coronavirus.
Hint 4 C titled Brilacidin–a human AMP peptidomimetic
Hint 5 B is a schematic of 3 Brilacidin molecules attaching to a viral capsid as you look from left to right you see the Brilacidin disrupting the membrane as more Brilacidin molecules attach the membrane is completely disrupted. A second schematic shows a blue viral capsid being disrupted.
Hint 6 An EM with 2 images ON the L is a cross section of the viral particle the on the R shows 2 disrupted viruses.
If you need any more help let me know.
GLTA Farrell
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