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Re: smokey4 post# 129270

Friday, 11/13/2020 1:44:22 PM

Friday, November 13, 2020 1:44:22 PM

Post# of 232882
What they're seeing in that study is antibodies against Interferon alpha and Interferon omega having a negative effect. Those interferons induce virus killing cells so with antibodies shutting them down the body is not killing off the virus effectively. So you have proliferation of the virus and nothing shutting down the cytokine storm.

Leronlimab downregulates Interferon gamma which is responsible along with IL-6 in macrophage recruitment that causes inflammation along with other inflammatory cytokines, shutting down the cytokine storm. It also boosts CD-8+ T-cells to fight the virus. By downregulating neuropilin-1 it also blocks a secondary COVID-19 entry site. Leronlimab also most likely works as an antiviral by disruption of the mTOR-1 pathway.

"Don’t have a clue as how to treat him. - ROCKLEO"

Has Dexamethasone been tried for the sepsis?
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