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Sunday, 11/08/2020 1:41:24 PM

Sunday, November 08, 2020 1:41:24 PM

Post# of 4867
Remdesivir should be tested in combination with brilacidin ASAP

combination of brilacidin with remdesivir at 10µM and 2.5µM concentrations, respectively, reduced the viral infectious titer by >99%, thus providing a highly effective inhibition profile (Figure 5B) and achieving greater inhibition than with either compound alone. This synergistic inhibition continued to remain higher than 99% when the concentrations of both compounds were equal (2.5µM each) (Figure 5C).



https://www.biorxiv.org/content/10.1101/2020.10.29.352450v1.full

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