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Re: dewophile post# 235452

Friday, 11/06/2020 6:28:04 AM

Friday, November 06, 2020 6:28:04 AM

Post# of 252407

Whatever biomarker and stopping criteria ASMB used clearly failed.

The stopping criterion was undetectable pgRNA in the blood, based on a proprietary, sensitive assay. However, undetectable pgRNA in the blood does not imply that viral replication in hepatocytes has ceased. ASMB uses a blood assay because liver biopsies are unduly invasive.

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