Whatever biomarker and stopping criteria ASMB used clearly failed.
The stopping criterion was undetectable pgRNA in the blood, based on a proprietary, sensitive assay. However, undetectable pgRNA in the blood does not imply that viral replication in hepatocytes has ceased. ASMB uses a blood assay because liver biopsies are unduly invasive.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”
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