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Re: sunspotter post# 331440

Tuesday, 11/03/2020 12:46:04 PM

Tuesday, November 03, 2020 12:46:04 PM

Post# of 402865
The likely protocol is to add Brilacidin to Remdesivir as treatment. It would be unethical have an unproven drug go against any standard of care along with a placebo group. Brilacidin has tested as a combination with Remdesivir, so the grouping would be Remdesivir plus B and Remdesivir plus placebo. The R
+ B group would then have an escalation for only B to find optimization. The outcomes would then look for increased efficacy over R alone. Remdesivir has such a low benefit over no treatment that increased benefit is a very low bar.

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