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https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3665228
In order to identify potential referral bias and confounding based on severity, Rothman score and WHO ordinal scale upon admission, together with Sequential Organ Failure Assessment Score (SOFA), at time of ICU admission was compared between aviptadil-treated and control patients (Table 2). Rothman index is a continuous predictor of impending mortality that is implemented as part of the electronic medical record system.
At hospital admission there were no significant differences in age gender, or Rothman index. At ICU admission, however, the Rothman
index (16.5(SD 23.7) vs. 56.9 (SD 26.1);P<0.001) and SOFA score (10.6 (SD3.7) vs. 4.3 (SD 2.2); P<.001) for aviptadil-treated patients was significantly worse than for control patients (Table 1 – detailed data reproduced in online Table 1a).
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