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Re: nelskof post# 11910

Wednesday, 10/21/2020 4:44:44 PM

Wednesday, October 21, 2020 4:44:44 PM

Post# of 16706
To clarify: A sample size calculation is just a small portion of trial design. I agree, they use 2b to determine sample size for phase 3 (because 2b gives them an idea of the expected reduction in symptoms necessary to be considered clinically significant), but the way they go about delivering the medication, testing the patients, collecting the data, will be similar.

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