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Post# of 252499
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Re: DewDiligence post# 235091

Wednesday, 10/14/2020 12:02:59 PM

Wednesday, October 14, 2020 12:02:59 PM

Post# of 252499
The phase 2 trial also didn't show dose response, see page 19 of https://investors.revance.com/static-files/fa582118-0191-44ae-b904-bb3d91e0fc1c

Look at the results in week 12, the higher dose (purple line) shows smaller reduction from baseline.

I would have thought page 17 of the current phase 3 results, https://investors.revance.com/static-files/6e3e48cd-84a0-4bf4-8319-4874c1aba9db, is important, lower dose implies significantly smaller rate of dsyphagia, 1.6% compared to 3.9% at the higher dose a small fraction of the rate (13 - 19%) for competitor products.



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