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Wednesday, October 14, 2020 10:56:39 AM
Nader update said over 50 deaths with N of 220 which gives mortality ranges from 23-27%, but let's ignore that bc, at this point, its moot
LL:Placebo/SOC 2:1
So for n of 195: 130:65 LL:Placebo/SOC
Most recent placebo severe to critical mortality rates range from 13 (Remdesivir trial) to 26% (HCQ trial) to 28% (Emory).
So let's use the 8k of n=195/D=45
Placebo let's say 27.5% death rate to give upper bound range of recent trials
Placebo/SOC is 18 deaths (18/65=27.5%)
LL is 27 deaths (45-18=27)
That is a p-value of 0.15, which is not close to stat sig
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