N.F.L. Week 3 Predictions: Our Picks Against the Spread With a matchup between the Ravens and the Chiefs looming on Monday, the rest of the week feels like an appetizer.
Dallas Cowboys at Seattle Seahawks, 4:25 p.m., Fox
Line: Seahawks -4.5 | Total: 55.5
It would be easier to feel good about the Cowboys (1-1) and their huge comeback victory against Atlanta last week if they had not fallen behind, 29-10, in the first place. There is clearly something amiss for the Dallas defense, and facing Russell Wilson and the Seahawks (2-0) in Seattle is not a good time to work through your issues. Pick: Seahawks -4.5
San Francisco 49ers at Giants, 1 p.m., Fox
Line: 49ers -4.5 | Total: 40.5
The 49ers (1-1) will definitely be without quarterback Jimmy Garoppolo, tight end George Kittle, defensive ends Nick Bosa and Solomon Thomas, cornerback Richard Sherman, center Weston Richburg and running back Tevin Coleman. They’ll likely be without running back Raheem Mostert. And they’re favored by 4.5 points on the road. The Giants (0-2) stink. Pick: 49ers -4.5
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