Quick comparison of PFE/BNTX, MRNA protocols: • PFE/BNTX has four interim looks (at 32, 62, 92, and 120 events); MRNA has two interim looks (at 53 and 106 events). • PFE/BNTX has the final analysis at 164 events; MRNA has the final analysis at 151 events. • PFE/BNTX has futility tests at the first three interim looks; MRNA does not have any futility tests. • The definition of an “event” is slightly different in the two protocols (but probably not different enough to matter from a practical standpoint). PFE/BNTX protocol (see p.103): https://t.co/w0TU1yVe7T?amp=1 MRNA protocol (see p.98): (https://t.co/The04HDHmE?amp=1