Relief Therapeutics Holding AG (RLFTF)

[ratna1]

Good Morning @Kiwi, @MD2Trader an d@All!
While wait for the first study results I thought it pertinent to bring back focus to the scientific and medical side of RLF100 as there are numerous papers and amazing studies that already have been already published and 2 NEW studies to begin in Basle, Switzerland and Freiburg,Germany!

Before I go into this however I would like to ask all our contributors here with a scientific and medical backgrounds if you have come across any research discussing the usage and impact of Aviptadil for thrombosis and/or pulmonary embolism?
I would appreciate any insights regarding these applications!

Here are a wide range of studies that took place e.g. for sarcoidosis, inflammation and even as adjunct therapy for cancer patients.

https://pubmed.ncbi.nlm.nih.gov/20442436/

https://pubmed.ncbi.nlm.nih.gov/16312132/

https://pubmed.ncbi.nlm.nih.gov/16508968/

https://www.uniklinik-freiburg.de/presse/pressemitteilungen/detailansicht/2058-hormon-inhalation-stoppt-schwere-nebenwirkung-von-immun-krebstherapie.html?fbclid=IwAR2Wx7usysrBoVl7scw3rVvfBZkMGshtKagJZPBb0xoqGfaYfiR9cE0G_vE

https://www.nejm.org/doi/10.1056/NEJMc2000343

You might already have seen these but for the sake of Newcomers I add them anyway:

https://poseidon01.ssrn.com/delivery.php?ID=990100103003010089094028019015005007060083047068050089011068097123008106094123090018020025118033005042003064078024110084123092108038011069020027091114023005085119001001087082094112067092019093069074023127015020068107081114019092005111119079030066124007&EXT=pdf

https://www.cureus.com/articles/39133-icosapent-ethyl---a-successful-treatment-for-symptomatic-covid-19-infection

We even made it to the WIKI-Verse but I feel that article might benefit from some editing…

https://en.wikipedia.org/wiki/Aviptadil

Early in Q4 a new study on the effects on OVID19 is about to recruit in Basel- Switzerland/
conducted by reputable Prof. Dr. Jörg Leuppi, Cantonal Hospital, Basel

https://clinicaltrials.gov/ct2/show/NCT04536350?term=aviptadil&draw=2&rank=1

And the University Hospital Freiburg will study the effect on sarcoidosis after having completed trials on the effects of Aviptadil / RLF 100 on pneumonia in cancer patients:


Hormon-Inhalation stoppt schwere Nebenwirkung von Immun-Krebstherapie
https://www.uniklinik-freiburg.de/presse/pressemitteilungen/detailansicht/2058-hormon-inhalation-stoppt-schwere-nebenwirkung-von-immun-krebstherapie.html?fbclid=IwAR2Wx7usysrBoVl7scw3rVvfBZkMGshtKagJZPBb0xoqGfaYfiR9cE0G_vE
It was published in the New England Journal of Medicine . 
that’s the Gold standard dfor Medical publishingg:
https://www.nejm.org/doi/10.1056/NEJMc2000343

Further studies on sarcoidosis are being set up

Einfluss von Aviptadil (Vasoaktives Intestinales Peptid)-Inhalation auf die immunologische Aktivität der Aveolarmakrophagen bei Sarkoidose - Klinische Studie Sarkoidose - Viomedo

https://www.viomedo.de/klinische-studien/1829/einfluss-aviptadil-vasoaktives-intestinales-peptid-inhalation-immunologische-aktivitaet-aveolarmakrophagen-sarkoidose

Here are other ongoing or recruiting trials:

https://clinicaltrials.gov/ct2/results?cond=&term=aviptadil&cntry=&state=&city=&dist=

https://clinicaltrials.gov/ct2/results?cond=&term=&type=&rslt=&age_v=&gndr=&intr=+RLF-100+%28aviptadil%29&titles=&outc=&spons=&lead=&id=&cntry=&state=&city=&dist=&locn=&rsub=&strd_s=&strd_e=&prcd_s=&prcd_e=&sfpd_s=&sfpd_e=&rfpd_s=&rfpd_e=&lupd_s=&lupd_e=&sort=

Inhaled Aviptadil for the Prevention of COVID-19 Related ARDS - Full Text View - ClinicalTrials.gov



Inhaled Aviptadil for the Prevention of COVID-19 Related ARDS - Full Tex...
Inhaled Aviptadil for the Prevention of COVID-19 Related ARDS - Full Text View.



Einfluss von Aviptadil (Vasoaktives Intestinales Peptid)-Inhalation auf ...


Search of: aviptadil - List Results - ClinicalTrials.gov


Search of: aviptadil - List Results - ClinicalTrials.gov


Numerous Studies in Print:

The neuropeptides VIP and PACAP inhibit SARS-CoV-2 replication in monocytes and lung epithelial cells, decrease the production of proinflammatory cytokines, and VIP levels are associated with survival in severe Covid-19 patients


The neuropeptides VIP and PACAP inhibit SARS-CoV-2 replication in monocy...
Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus ...


https://www.neurorxpharma.com/wp-content/uploads/2020/07/Javitt-VIP-Perspective-July-22-2020.pdf

https://poseidon01.ssrn.com/delivery.php?ID=990100103003010089094028019015005007060083047068050089011068097123008106094123090018020025118033005042003064078024110084123092108038011069020027091114023005085119001001087082094112067092019093069074023127015020068107081114019092005111119079030066124007&EXT=pdf



cdn.fbsbx.com/v/t59.2708-21/117307139_226766902013584_1138053463694780524_n.pdf/JG-Youssef-VIP-in-treatment-of-Critical-COVID-19.pdf?_nc_cat=107&_nc_sid=0cab14&_nc_ohc=SXm3Ufr75vYAX97n_kZ&_nc_ht=cdn.fbsbx.com&oh=c7f60686d6a909e2e8d56e76daa1d314&oe=5F3EE7C8&dl=1 .


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