Revive Therapeutics Ltd (RVVTF)

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Colchicine is good but....

From another poster, thought of sharing it here......

Even though Colchicine has been in use for many years for gout users, it has many side affects from mid to long term use.
Case in point, my Father has gout and was a frequent user of Colchicine to manage his inflammations. A change in diet is definitely recommended to help mitigate the flares ups; low to no red meat protein, shellfish and alcohol while eating more alkaline foods and plenty of water are best as a starting point. Some are successful on this diet and some are not. For those who require Colchicine to temper all their small and big flare up's they eventually add to future problems down the road where the effectiveness of the drug is lessened over time so, it's necessary to up the prescribed dosage to achieve on-going results.
My father hit those moments in requiring consecutive higher dosages in the last 15yrs and longer to the point he was developing problems with his kidneys so, another medication was added to support his low functioning kidneys. What a vicious cycle to be caught in!
Today, he doesn't rely on the Colchicine and kidney meds anymore for his gout; just managed through diet that's even more restrictive and selective with food options compared to before.
This at a huge physical cost where he now has a slight hobble on one foot and some crooked finger tips with his joints calcified. Flare up's are still slight but unavoidable. His kidneys are worse then before and not suitable for organ transplant due to age while on verge of needing dialysis. Pray it never leads to this!
As a personal observer and someone who also has mild gout by hereditary nature, without a doubt, I have much higher regards for Bucillamine in short and long term use.