Friday, September 04, 2020 1:12:30 PM
"From this information and knowledge of other viruses like HIV-AIDS, Ebola, Influenza, Hepatitis C, or Malaria (4, 5), we have suites of anti-viral and other compounds that can potentially mitigate the damage of the virus on the body, including Remdesivir, Tocilizumab, Favipiravir, Galidesivir, Brilacidin, and Dexamethasone (5). In particular, Remdesivir, which resembles the structure of an HIV reverse-transcriptase inhibitor, has shown promise for reducing recovery time of patients in acute stages, and the steroid Dexamethasone, used widely to fight serious inflammatory reactions, was shown to reduce Covid-19 deaths. Drugs that block spike, membrane, or envelope proteins on the viral shell of coronaviruses are actively being sought, and some are being investigated in clinical trials."
Pre-print is titled: Structure-Altering Mutations of the SARS-CoV-2 Frame Shifting RNA Element
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