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Re: maxinvest post# 320304

Monday, 08/24/2020 5:12:49 PM

Monday, August 24, 2020 5:12:49 PM

Post# of 403134
Aviptadil isn't much of an antiviral, IMO. It's more of a hormone / immunomodulator, that works mainly by increasing lung surfactant (including some surfactant proteins with defensin like activity).

https://www.biorxiv.org/content/10.1101/2020.07.25.220806v2.full

Showed in Vero and human lung cells that VIP/aviptadil only reduced viral load by ~40%, so there is no IC50 if the definition if 50% reduction of viral load.

They had very impressive EIND/EA data thus far, though, and pretty good safety.
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