Relief Therapeutics Holding AG (RLFTF)

[mc67]

$RLFTF Reminder. 6pm est tonight. Coronavirus (COVID-19)

Aviptadil (RLF-100) For COVID-19: 21 Patients With Severe Refractory COVID Showing Improvements!

WhiteBoard style discussion on a pre-print case series (partially authored by the company that owns Aviptadil) on 21 patients with severe refractory COVID-19 all on ventilators and several on ECMO who failed multiple other therapies including remdesevir, tocilizumab, convalescent plasma, etc.

They were granted FDA emergency use authorization for intravenous Aviptadil (RLF-100). They saw significant improvements in the PaO2:FiO2 ratio, improvements in lung imaging, decreases in inflammatory markers, and improvements in the WHO ordinal scale. At 21 days, there was only a single death secondary to COVID-19 in this severely ill population.

Many had been discharged home on room air! Of note, this is a case series in pre-print partially authored by the company that owns Aviptadil, so there are many potential limitations!