electroCore, Inc. (ECOR)

[Fezziwig2008]

ECOR “As a result, activating the anti-inflammatory reflex mechanism modulates the exaggeration of pro-inflammatory cytokine effects (Reardon 2016; Zila et al. 2017; Chu et al. 2020). Although no drug that can be clinically effective on a7nAChR with minor side effects in humans has been discovered yet, however, vagus nerve stimulation has been used for therapeutic purposes. It can improve sepsis, lung injury, rheumatoid arthritis, stroke, traumatic brain injury, obesity, diabetes, cardiovascular control, and pain management (Zila et al. 2017).
Activating the cholinergic anti-inflammatory pathway can be a therapeutic strategy, especially for respiratory diseases and their comorbidities (Yamada and Ichinose 2018). Put together, activating the vagus nerve may demonstrate positive therapeutic effects on COVID-19 symptoms through antiinflammatory mechanisms.”

https://scholar.google.com.hk/scholar?as_ylo=2020&q=vagal+stimulation+and+COVID+19&hl=en&as_sdt=0,33#d=gs_qabs&u=%23p%3DcNoIlHFn7o8J