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Alias Born 08/01/2020

Re: bobshmob post# 12550

Saturday, 08/01/2020 4:31:26 AM

Saturday, August 01, 2020 4:31:26 AM

Post# of 43393

Will it be effective for mild, moderate, severe, critical cases?


> From the MOA of anti-GMCSF, I think lenzilumab will work in mild/ moderate cases, preventing some patients progressing into severe/ critical stage. Once you have cytokine storm induced tissue damage, it is probably very difficult to recover.

What are people thinking about the BET trials in combo with remdesivir? It seems like remdesivir should be easy to beat


> It is a logical combination, remdesivir inhibit virus replication, and anti-GMCSF prevent lethally consequences of virus infection (cytokine storm).
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