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Re: Borel Fields post# 97520

Thursday, 07/23/2020 12:01:47 AM

Thursday, July 23, 2020 12:01:47 AM

Post# of 232987
After seeing the SAE data, I'm 90:10 or 95:5 that m/m primary outcome will be statistically significant. For crying out loud, the very crude measures of SAEs (p = 0.06) and AEs (p = 0.08) are very close to statistically significant. The primary outcome is a more sophisticated measure with more information and designed specifically to detect clinically and statistically significant differences. It is certainly possible there won't be a significant difference, but it would surprise me more than an 80:20 proposition would if it failed.
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