electroCore, Inc. (ECOR)

[Fezziwig2008]

ECOR works in GI Tract -Open-label pilot study: Non-invasive vagal nerve stimulation improves symptoms and gastric emptying in patients with idiopathic gastroparesis

in Neurogastroenterology and Motility 32(7):e13769 · December 2019
... In a proof-of-concept study, noninvasive VNS was shown to decrease GSCI in 35% of Gp subjects using stimulator 3 times a day for greater than 3 weeks [80]. In an open-label study of idiopathic Gp subjects, noninvasive VNS for 4 weeks was associated with improvement of GSCI and gastric emptying

"Short-term non-invasive vagal nerve stimulation led to improved cardinal symptoms and accelerated gastric emptying in a subset of patients with idiopathic gastroparesis. Responders had more severe gastric delay at baseline and clinical improvement correlated with duration of therapy, but not with improvements in gastric emptying."