Humanigen Inc (HGENQ)

[LongTkt]

Both drugs are a lot alike Part2.

The cytokine storm is bad and the human body keeps it controlled under lock & key. Lenzilumab binds to the key so it doesn't fit in the lock. Leronlimab binds to the lock so the key doesn't fit. If the biological process cannot be unlocked, then there is no cytokine storm.

1. GM-CSF is an inflammatory cytokine signaling molecule that promotes inflammation response by cells.

2. CCR5 is a type of receptor on a few types of white blood cells (including macrophage and T cells) and plays a role in inflammatory responses to infection.

3. Therapies to treat inflammatory diseases either neutralize inflammatory cytokines or their receptors.

4. Lenzilumab binds to/neutralizes the GM-CSF inflammatory cytokine.

5. Leronlimab binds to/neutralizes the CCR5 receptor.


Thanks for the nudge to do this from Fezziwig2008!