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Friday, July 17, 2020 3:59:54 PM
I'm uncertain, but I believe that was before a decision was made to go into trials for Covid-19. I would hope they could come out of Covid-19 with an approval from a rather small Phase 2, but it's possible they're guessing, or know that it will require a larger trial, possibly expanding on the data from the Phase 2.
I believe the pneumonia market to be huge, but the trial in general for pneumonia would be an enormous Phase 3 as most people who acquire pneumonia do survive it. Covid-19 gives us the opportunity to prove what the drug can do in a deadlier form of pneumonia, but if approved in it, you can bet it will be used off label for other forms until such time as it's proven worthy of a label expansion.
I believe regardless of what the initial approval for PLX-PAD is, it will be tried off label for many things, and often found to be effective. Covid-19 may gain initial approval, but don't write off any of the other trials, I believe we'll see approvals as well as they move forward.
Gary
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