Innovation Pharmaceuticals Inc (IPIX)

[Lemoncat]

Did P mild-to-moderate share the same fatal flaw that B-ABSSSI purportedly suffers...market's not big enough

No, the signal seen in the Prurisol Phase 2a trial was cherry-picked with optimism amid a very small numbers of patients. It was a gamble and in the end it was a victim of drawing conclusions based on a very small N. Mild-to-moderate psoriasis has much more waxing/waning and is subject to significant placebo effect. It's obvious once we got into the moderate-severe cases that Prurisol had little to no effect. Prurisol probably did not work on mild-moderate psoriasis, we simply got lucky (or really unlucky in hind sight) by identifying a subset of of arm in the phase 2a which led us into a debacle of a phase 2b.

B-ABSSSI on the other hand had a rock solid high-powered phase 2B which was a stellar success. What has prevented a partnership? We haven't been given an answer but the market must not be as rosy as it was for Cubicin otherwise we would have made a deal by now.

Go IPIX!