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Re: Borel Fields post# 89428

Wednesday, 07/01/2020 12:10:15 AM

Wednesday, July 01, 2020 12:10:15 AM

Post# of 233137
For our purposes, Tocilizumab is a non-starter since it's an IL-6 inhibitor only. Leronlimab targets IL-6 and the CCL5 (Rantes)/CCR5 pathway.
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Borel Fields Tuesday, 06/30/20 11:41:01 PM
Re: bobshmob post# 89359 0
Post # of 89432
Some good outcomes on tocilizumab, but not randomized, as paragraph 2 of the Lancet paper notes: "a non-randomly selected subset of patients also received tocilizumab."

No question, the list of possible storm-treating drugs is narrowing to leronlimab (first with randomized trial results), tocilizumab and lenzilumab. And everyone understands we need storm-treating drugs.
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