Sunday, June 28, 2020 10:20:01 PM
https://www.nejm.org/doi/full/10.1056/NEJMc2011117
Let me first mention I am a share holder. I did sell half of my 100k shares at profit.
Looks like in this study Lorenlimab works, decreasing IL6. However decreasing IL6 may worsen outcomes or at best not change them, except in one patient with very low levels. 5 of the 6 Lorenlimab patients had bad outcomes. Either dead or put on mechanical ventilation. This is a very small sample size of covid 19 patients with renal transplants. All were given the medicine after IL6 was found to be elevated but before respiratory failure. Either way the results of the phase 3 severe study may be a concern.
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