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Wednesday, 06/10/2020 8:59:53 PM

Wednesday, June 10, 2020 8:59:53 PM

Post# of 232882
NEJM today. Remdesivir compassionate use. Not randomized, so no comparisons in the abstract, but better outcomes than I would have guessed from a population this sick.

"Of the 53 patients whose data were analyzed, 22 were in the United States, 22 in Europe or Canada, and 9 in Japan. At baseline, 30 patients (57%) were receiving mechanical ventilation and 4 (8%) were receiving extracorporeal membrane oxygenation.

During a median follow-up of 18 days, 36 patients (68%) had an improvement in oxygen-support class, including 17 of 30 patients (57%) receiving mechanical ventilation who were extubated.

A total of 25 patients (47%) were discharged, and 7 patients (13%) died; mortality was 18% (6 of 34) among patients receiving invasive ventilation and 5% (1 of 19) among those not receiving invasive ventilation."
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