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Re: tikotiko post# 83048

Sunday, 06/07/2020 9:44:20 PM

Sunday, June 07, 2020 9:44:20 PM

Post# of 232933
Right on. I would caution we may not get a one-sided test - Remdesivir deserved a two-sided test because it might kill more people. We don't, but.... That would typically require one less death in the leron group.

The deaths in the placebo group will depend on the severe vs. critical mix. We've seen estimates of critical death rates as high as 88%. I have no idea for severe.

What are are the group's upsides/downsides to a guess of 65% (=11/17) based on half severe at 50% and half critical at 80%?
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